Essential fatty acids explained

Image source: https://www.eufic.org/en/whats-in-food/article/the-importance-of-omega-3-and-omega-6-fatty-acids

What they are and how to make sure you eat enough.

There are two fats that humans have to eat as the body cannot make them and they are required for specific functions. They are called omega-3 (ω-3) and omega-6 (ω-6) and known as essential fatty acids (EFA’s) for this reason. They are both polyunsaturated fatty acids (PUFA’s) which means that they have more than one double bond between their carbon back bone. They get their name from the carbon number where their first double bond appears (see pic).

In the diet omega-3 is found in flax, hemp, pumpkin and chia seeds as well as walnuts. The end products of omega-3 (ALA) that the body requires are called EPA and DHA. Fish already contains both which is why it is such a good source, as the body doesn’t need to convert it. The conversion from other sources is very small and many people struggle with it, hence the oily fish recommendation.

Omega-6 is found in vegetable oils from seeds of corn, sunflower, safflower, cotton and soybeans. It is also found in evening primrose oil, borage, starflower and blackcurrant oils. It is converted to a downstream product known as arachidonic acid (AA). This end product (AA) is freely available in meat, egg and dairy products.

Our intake of omega-6 tends to exceed omega-3 considerably due to the nature of most people’s diets and the relatively recent availability of vegetable and sunflower cooking oils. My parents are over 80 but my mum can still remember how she queued up in the grocers to buy a slab of butter, wrapped in greaseproof paper. Most processed foods and ready-made dressings, sauces and jars also contain omega-6.

Research scientist Simopoulos (2002) believes we historically consumed equal amounts of omega-3 and omega-6, a 1:1 ratio. We now consume 15-16.7 times as much omega-6.

Omega-3 and omega-6 fatty acids are however both important components of cell membranes. During the conversion process they produce downstream products (eicosanoids) which regulate our inflammatory responses. Omega-3 eicosanoids are known to have anti-inflammatory effects. The eicosanoids from omega-3 tend to be more anti-inflammatory and anti-coagulatory than omega-6, which produces both inflammatory and anti-inflammatory versions.

Omega-3 and omega-6 both utilise the same conversion enzyme (delta-6-desaturase) so theories have arisen that one process will deprive the other. A high omega-6 intake is thought to reduce the availability of this enzyme and so diminish our omega-3 conversion. This theory and the concept of an “ideal” ratio in the diet is contested but it is generally thought that a ratio of 4:1 (ω-6: ω-3) is optimum.

The European Food Safety Authority concluded that 250 mg a day of EPA and DHA was adequate. They also found that European intake was too low at between 20-40 mg per day for EPA and less than 100-130 mg per day for DHA.

It’s kind of difficult to think about ratio’s when you are out shopping or planning your menus, so this is the way I tend to advise clients. Providing your digestion is good then generally you can obtain enough EPA and DHA by consuming oily fish 2-3 times per week. Otherwise supplementation is likely the best option.

References

https://pubmed.ncbi.nlm.nih.gov/12442909

https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1461

https://www.eufic.org/en/whats-in-food/article/the-importance-of-omega-3-and-omega-6-fatty-acids

https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/recommended-dietary-reference-intakes-nutritional-goals-and-dietary-guidelines-for-fat-and-fatty-acids-a-systematic-review/5C2EDA7CD9C4EAB094F8499B2E122E75

Do your cells need an oil change?

Today’s modern diets can often mean we eat too much or too little fat, or frequently just the wrong type. Our cell membranes consist of lots of oil aka. fat. For optimal performance they require quite a specific ratio of different types of fats, especially with regard to the essential fatty acids (EFA’s), omega 3 and 6. If these are out of sync, cells can malfunction a bit like trying to run your car on the wrong type of oil or petrol.

Cell membranes are your cells’ border control. They control what gets in and what gets out. They act as both the gatekeeper and the hostess.

Every cell in your body has a cell membrane and your body has a lot of cells. Experts think we have in the region of 30 trillion, and we want every one of these to have a healthy cell membrane. If your cell membranes are working correctly, they will let micronutrients in and waste products out. As well as supervising which molecules can enter and exit, most cell metabolism takes place in, on, or around this location. It’s like your very own production line inside you, manufacturing energy and proteins, and churning out waste products such as urea and toxins.

The next thing to understand is that their structure is critical to how well they function. We don’t want them to be too rigid or nothing will get in, or out. We also don’t want them too soft and floppy. This might allow too much in or too much out and over time this could cause multiple issues.

So how can we nourish them and maintain their structure so they can function properly? Firstly, the fat they contain needs to be eaten, as the body cannot make it. Some of these fats have special functions such as the EFA’s. There are many arguments about the correct ratio of fats to eat in the diet but researchers generally agree that we tend to be more deficient in omega 3 which is found in fish, nuts, seeds and vegetable oils.

So by now I think you get the idea that I like my clients to achieve healthy cell membranes because “the stronger our cells the more resilient our selves”.

It’s easy to check our ratios with a simple finger prick test because the concentration in our blood has been found to strongly reflect our dietary intake. The current European average for our omega 3 percentage is less than 4% but research confirms that 8% is optimum, and that this ratio is associated with a 90% reduction in risk of sudden cardiac death.

There is nothing like analytics to demonstrate to my clients (and me) that we either need to work harder on our diet or take targeted supplements to give our cells what they need to function tip top.

https://pubmed.ncbi.nlm.nih.gov/18541601